Methoxychlor Disrupts Uterine Hoxa10 Gene Expression
نویسندگان
چکیده
منابع مشابه
Methoxychlor disrupts uterine Hoxa10 gene expression.
Methoxychlor (MXC) is a pesticide that has adverse effects on reproductive capability in mice. MXC and its metabolites bind the estrogen receptor and function as endocrine disruptors. MXC diminishes the uterine decidual cell response, necessary for the support of pregnancy. Hoxa10 is an estrogen-regulated gene that is an essential mediator of the decidual response and necessary for pregnancy. H...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2005
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2005-0341